Research Associate in Systems Biology

Imperial College London Department of Bioengineering

United Kingdom

Job summary

Rodrigo Ledesma-Amaro (www.rlalab.org) is a group leader at Imperial College London working at the interface between synthetic biology and metabolic engineering with applications in biotechnology, biomedicine and biomaterials. The Research Associate position will be undertaken as part of an ERC grant held by Dr Ledesma-Amaro https://www.imperial.ac.uk/news/203013/four-imperial-engineers-erc-starting-grants/ . Collaborations with other members...

Job listing information

  • Reference ENG01485
  • Date posted 27 November 2020
  • Closing date 4 January 2021

Key information about the role

  • Location South Kensington Campus (map)
  • Position type Full time, fixed term
  • Salary £40,215 – £47,579 plus benefits
  • Department Department of Bioengineering
  • Category Researcher / Non Clinical Researcher

Job description

Job summary

Rodrigo Ledesma-Amaro (www.rlalab.org) is a group leader at Imperial College London working at the interface between synthetic biology and metabolic engineering with applications in biotechnology, biomedicine and biomaterials.

The Research Associate position will be undertaken as part of an ERC grant held by Dr Ledesma-Amaro https://www.imperial.ac.uk/news/203013/four-imperial-engineers-erc-starting-grants/ . Collaborations with other members of the group and project are expected, including the co-supervision of a PhD student.

The purpose of the role is to use cutting edge system biology tools, in particular single cell technologies in order to understand the principles underpinning cell to cell heterogeneity in microbial cell factories. Such heterogeneity is often responsible for low production yields as some cells will not produce as much as others. The project will combine state of the art techniques and innovative tools with industrial bioproduction.

In addition, your generated knowledge will be used to engineer heterogeneity in microbial populations which may guide research towards the generation of the next generation of cell factories.

As a Research Associate you will carry out research programmes in microbial systems biology and synthetic biology, undertake project management and/or supervise multi-disciplinary teams. In addition, you will be expected to submit publications to refereed journals.          

Duties and responsibilities

As part of a growing research group, you will:

  • Work on an exciting and timely project using state of the art techniques and methodologies in a collaborative working environment.
  • Carry out research programmes in microbial systems biology and synthetic biology, undertake project management and/or supervise multi-disciplinary teams.
  • Develop and broaden knowledge and expertise in a truly multidisciplinary project, which employs methods and principles from microbial molecular biology (CRISPR, Golden Gate, etc.) to metabolic modelling or bioinformatics.
  • Develop networking and collaboration channels and skills with both academic and industrial partners.

Essential requirements

As a Research Associate, you will have:

  • A PhD, or equivalent in Systems biology, Bioinformatics, Metabolic engineering, Synthetic Biology or a closely related area/discipline or equivalent research
  • Experience of research in systems biology, computational biology, bioinformatics, multi-omics, functional genomics, strain engineering or closely related area
  • Experience in RNAseq or other omics with Experience in single cell RNAseq or other single cell techniques
  • Experience with scientific programming languages such as Matlab or Python and/or modelling of dynamic biosystems
  • Knowledge and understanding of fundamental principles of biochemical and molecular biological systems

Further information

This post is full-time and fixed term for 24 months (initially).

*Candidates who have not yet been officially awarded their PhD will be appointed as Research Assistant within the salary range £35,477 - £38,566 per annum.

For informal enquiries about the post please contact Dr Ledesma-Amaro r.ledesma-amaro@imperial.ac.uk

Our preferred method of application is online via our website. Please click ‘apply’ below or go to http://www3.imperial.ac.uk/employment. (Select “Job Search” then enter the job title or vacancy reference number into “Keywords”). Please complete and upload an application form as directed quoting reference number ENG01485 Further information is also available on the job description

Closing date: 04/01/2021

Any queries regarding the application process should be directed to Michelle McCartney at m.mccartney@imperial.ac.uk.

For technical issues when applying online please email recruitment@imperial.ac.uk

The College is a proud signatory to the San-Francisco Declaration on Research Assessment (DORA), which means that in hiring and promotion decisions, we evaluate applicants on the quality of their work, not the journal impact factor where it is published. For more information, see https://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-evaluation/

The College believes that the use of animals in research is vital to improve human and animal health and welfare. Animals may only be used in research programmes where their use is shown to be necessary for developing new treatments and making medical advances. Imperial is committed to ensuring that, in cases where this research is deemed essential, all animals in the College’s care are treated with full respect, and that all staff involved with this work show due consideration at every level.

http://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-integrity/animal-research

Imperial College is committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment. We are an Athena SWAN Silver award winner, a Stonewall Diversity Champion, a Disability Confident Employer and work in partnership with GIRES to promote respect for trans people.


In your application, please refer to Polytechnicpositions.com

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